Nicholas M Anstey Selected Research

Nitric Oxide Synthase (NO Synthase)

1/2016	Pharmacokinetic-Pharmacodynamic Model for the Effect of l-Arginine on Endothelial Function in Patients with Moderately Severe Falciparum Malaria.
1/2016	Asymmetric Dimethylarginine in Adult Falciparum Malaria: Relationships With Disease Severity, Antimalarial Treatment, Hemolysis, and Inflammation.
2/2011	Asymmetric dimethylarginine, endothelial nitric oxide bioavailability and mortality in sepsis.
4/2010	Increased asymmetric dimethylarginine in severe falciparum malaria: association with impaired nitric oxide bioavailability and fatal outcome.
2/2010	Malaria severity and human nitric oxide synthase type 2 (NOS2) promoter haplotypes.
1/2010	HPLC analysis of asymmetric dimethylarginine, symmetric dimethylarginine, homoarginine and arginine in small plasma volumes using a Gemini-NX column at high pH.
12/2008	Pharmacokinetics of L-arginine in adults with moderately severe malaria.
12/2004	Nitric oxide production and nitric oxide synthase activity in malaria-exposed Papua New Guinean children and adults show longitudinal stability and no association with parasitemia.
11/2003	Plasma interleukin-12 in malaria-tolerant papua new guineans: inverse correlation with Plasmodium falciparum parasitemia and peripheral blood mononuclear cell nitric oxide synthase activity.
7/2003	Nitric oxide production and mononuclear cell nitric oxide synthase activity in malaria-tolerant Papuan adults.

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Nicholas M Anstey Research Topics

Disease

104	Malaria 10/2022 - 01/2002
53	Falciparum Malaria (Plasmodium falciparum Malaria) 10/2022 - 07/2002
47	Infections 10/2022 - 12/2002
26	Vivax Malaria 01/2022 - 12/2002
19	Parasitemia 01/2021 - 09/2002
16	Hemolysis 10/2022 - 10/2007
13	Cerebral Malaria 10/2021 - 02/2003
13	Sepsis (Septicemia) 04/2018 - 05/2004
8	Anemia 04/2020 - 05/2005
7	Acute Kidney Injury (Acute Renal Failure) 10/2022 - 06/2015
7	Melioidosis 01/2020 - 09/2003
7	Tuberculosis (Tuberculoses) 01/2019 - 07/2008
6	Fever (Fevers) 10/2020 - 09/2002
5	Hyperemia 11/2016 - 11/2008
4	Septic Shock (Toxic Shock Syndrome) 12/2021 - 01/2004
4	Pneumonia (Pneumonitis) 01/2020 - 09/2003
4	Glucosephosphate Dehydrogenase Deficiency 01/2019 - 12/2011
3	Coma (Comas) 10/2021 - 02/2013
3	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 10/2020 - 12/2005
3	Thrombocytopenia (Thrombopenia) 04/2020 - 01/2015
3	Convalescence 01/2020 - 07/2013
3	Pulmonary Tuberculosis 01/2017 - 01/2013
3	Inflammation (Inflammations) 01/2017 - 01/2015
3	Critical Illness (Critically Ill) 12/2013 - 01/2010
3	Acidosis 03/2010 - 08/2002
2	Acute malaria 01/2020 - 06/2009
2	Hypoxia (Hypoxemia) 03/2019 - 02/2013
2	Bacterial Infections (Bacterial Infection) 01/2018 - 01/2016
2	Disease Progression 01/2017 - 09/2002
2	Vascular Diseases (Vascular Disease) 10/2014 - 02/2011
2	Communicable Diseases (Infectious Diseases) 08/2014 - 02/2010
2	Ischemia 02/2013 - 10/2007

Drug/Important Bio-Agent (IBA)

34	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2021 - 01/2002
19	Pharmaceutical PreparationsIBA 01/2022 - 07/2002
19	Chloroquine (Aralen)FDA LinkGeneric 01/2021 - 07/2002
19	Arginine (L-Arginine)FDA Link 01/2019 - 02/2003
18	artemisinin (artemisinine)IBA 01/2021 - 12/2002
17	ArtesunateIBA 01/2021 - 12/2002
15	Hemoglobins (Hemoglobin)IBA 10/2022 - 05/2005
15	Antimalarials (Antimalarial Agents)IBA 01/2020 - 09/2002
12	Nitric Oxide Synthase (NO Synthase)IBA 01/2016 - 11/2002
11	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2005
11	Primaquine FDA Link 11/2020 - 10/2009
8	CytokinesIBA 02/2021 - 09/2002
8	Anti-Bacterial Agents (Antibiotics)IBA 01/2020 - 09/2003
8	Lactic Acid (Lactate)FDA LinkGeneric 03/2019 - 10/2007
7	AntibodiesIBA 01/2022 - 09/2002
7	piperaquineIBA 12/2021 - 10/2012
7	artenimol (dihydroartemisinin)IBA 12/2021 - 10/2012
7	Interleukin-10 (Interleukin 10)IBA 01/2019 - 05/2005
6	Immunoglobulin G (IgG)IBA 01/2022 - 09/2002
6	VaccinesIBA 01/2022 - 08/2006
6	N,N-dimethylarginine (asymmetric dimethylarginine)IBA 01/2021 - 04/2010
6	HLA-DR Antigens (HLA-DR)IBA 01/2020 - 08/2015
6	Angiopoietin-2IBA 06/2018 - 11/2008
5	CreatinineIBA 10/2022 - 05/2005
5	Biomarkers (Surrogate Marker)IBA 01/2021 - 11/2008
5	AntigensIBA 01/2018 - 06/2009
5	Histidine (L-Histidine)FDA Link 01/2018 - 01/2012
4	Acetaminophen (Paracetamol)FDA LinkGeneric 10/2022 - 01/2018
4	Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA 04/2019 - 03/2017
4	Oxygen (Dioxygen)IBA 03/2019 - 02/2013
4	Amino Acids FDA Link 01/2019 - 06/2006
4	Interleukin-6 (Interleukin 6)IBA 01/2017 - 07/2010
4	ArginaseIBA 01/2016 - 04/2014
3	RNA (Ribonucleic Acid)IBA 01/2020 - 01/2017
3	Complement System Proteins (Complement)IBA 11/2019 - 11/2018
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2019 - 05/2005
3	EnzymesIBA 06/2017 - 02/2010
3	Vitamin D FDA LinkGeneric 01/2017 - 07/2008
3	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2015 - 04/2013
2	Plasmodium falciparum erythrocyte membrane protein 1IBA 01/2022 - 05/2016
2	PterinsIBA 10/2021 - 03/2015
2	OsteoprotegerinIBA 01/2020 - 06/2018
2	InterferonsIBA 01/2020 - 01/2011
2	Immunoglobulin M (IgM)IBA 01/2019 - 09/2002
2	Lumefantrine Drug Combination Artemether (Coartem)FDA Link 01/2018 - 01/2017
2	KynurenineIBA 01/2017 - 01/2011
2	Mefloquine (Lariam)FDA LinkGeneric 02/2016 - 01/2016
2	Interleukin-12 (IL 12)IBA 01/2016 - 11/2003
2	Messenger RNA (mRNA)IBA 01/2016 - 08/2014
2	BiopterinsIBA 03/2015 - 03/2015
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 03/2015 - 07/2010
2	Phenylalanine (L-Phenylalanine)FDA Link 03/2015 - 06/2006
2	7,8-dihydrobiopterinIBA 03/2015 - 03/2015
2	sapropterin (tetrahydrobiopterin)FDA Link 03/2015 - 03/2015
2	E-SelectinIBA 01/2015 - 07/2010
2	Quinine (Quinson)FDA Link 01/2014 - 06/2008
2	Essential Amino AcidsIBA 02/2011 - 01/2011
2	Lymphotoxin-alpha (Lymphotoxin)IBA 10/2010 - 07/2010
2	Bicarbonates (Hydrogen Carbonate)IBA 03/2010 - 09/2003
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 02/2010 - 12/2003
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2010 - 11/2008

Therapy/Procedure

33	Therapeutics 01/2021 - 12/2002
8	Aftercare (After-Treatment) 01/2022 - 05/2002
3	Splenectomy 01/2021 - 09/2016
3	Blood Transfusion (Blood Transfusions) 07/2016 - 11/2014
2	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2017 - 01/2015
2	Length of Stay 12/2015 - 02/2008
2	Resuscitation 01/2015 - 11/2014